There are times where SELinux just does not want to play nice. For instance, after installing ClamAV I began running into problems where if I did not turn off SELinux while ClamAV was running, then SMTP traffic would fail. To fix this issue we must first look at the messages file under /var/log. Within this file we will see error messages like:
setroubleshoot: SELinux is preventing cleanup (postfix_cleanup_t) "search" to ./clamav (clamd_var_lib_t).

Which tells you to run the command:
sealert -l a1bc9b39-80a2-4f2e-963f-12daf766a8d4

Usually the report is very good and diagnosing and telling you which booleans to activate, however in this instance we have to create our own module.

First: Download and install selinux-policy-devel
Second: Parse through the raw audit messages. We are looking for two things; message type and comm name.
Third: Run the ausearch command and pipe it to audit2allow
For instance: ausearch -m AVC --comm cleanup | audit2allow -M ClamAV

Once the files have been generated then run: semodule -i ClamAV.pp and see if the problem has been resolved. If not, tail the messages log again to see if there is any additional SEAlerts that you should be aware of.